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Home Antibody All anti-ROBO3 antibodies

Anti-ROBO3 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA303233 Goat Polyclonal Antibody against ROBO3 100ug $325 3-7 Days
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WB(1)

OriGene Data

Immunogen Peptide with sequence C-RRKQRKELSHYT, from the internal region of the protein sequence according to NP_071765.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Dog, Pig, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:32,000. WB: 0.5-1µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens roundabout, axon guidance receptor, homolog 3 (Drosophila) (ROBO3)
Alternative NameHGPPS; HGPS; RBIG1; RIG1
Database LinkNP_071765
Entrez Gene 64221 Human
Entrez Gene 489307 Dog
FunctionThought to be involved during neural development in axonal navigation at the ventral midline of the neural tube. In spinal chord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1 (By similarity). Required for hindbrain axon midline crossing
Related PathwayDruggable Genome Axon guidance

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA303233 (0.5µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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