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Home Antibody All anti-CNTFR antibodies

Anti-CNTFR Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303173 Goat Polyclonal Antibody against CNTFR 100ug $325 3-7 Days
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OriGene Data

Immunogen Peptide with sequence CRSNTYPKGFY, from the internal region of the protein sequence according to NP_671693.1; NP_001833.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Mouse. Expected from seq similarity: Human, Mouse, Rat, Dog Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:16,000. WB: 0.3-1µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameMus musculus ciliary neurotrophic factor receptor (Cntfr), transcript variant 1
Alternative NameCntfralpha
Database LinkNP_057882
Entrez Gene 1271 Human
Entrez Gene 12804 Mouse
Entrez Gene 313173 Rat
Entrez Gene 442941 Dog
FunctionThis gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA303173 (0.3µg/ml) staining of mouse brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


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