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Home Antibody All anti-AKR1C4 antibodies

Anti-AKR1C4 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303107 Goat Polyclonal Antibody against AKR1C4 100ug $325 3-7 Days
LC419725 AKR1C4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for AKR1C4 (NM_001818)
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OriGene Data

Immunogen Peptide with sequence DPKYQRVELNDGH-C, from the N Terminus of the protein sequence according to NP_001809.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:4,000. WB: 0.1-0.3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens aldo-keto reductase family 1, member C4 (AKR1C4)
Alternative Name3-alpha-HSD; C11; CDR; CHDR; DD-4; DD4; HAKRA
Database LinkNP_001809
Entrez Gene 1109 Human
FunctionThis gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq].
Related PathwayDruggable Genome Primary bile acid biosynthesisC21-Steroid hormone metabolismAndrogen and estrogen metabolismMetabolism of xenobiotics by cytochrome P450Metabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA303107 (0.1µg/ml) staining of human liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


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