Home Antibody All anti-ROBO1 antibodies
Also for ROBO1 (NM_001145844)
| Peptide with sequence C-GDVDLSNKINEMK, from the internal region of the protein sequence according to NP_002932.1; NP_598334.1.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow
||ELISA: 1:8,000. WB: 1-3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens roundabout, axon guidance receptor, homolog 1 (Drosophila) (ROBO1), transcript variant 3|
|DUTT1; FLJ21882; MGC131599; MGC133277; SAX3; FLJ21882; MGC131599; MGC133277; SAX3; axon guidance receptor; roundabout 1; roundabout, axon guidance receptor, homolog 1 (Drosophila)|
Entrez Gene 6091 Human
Entrez Gene 19876 Mouse
Entrez Gene 58946 Rat
Entrez Gene 487690 Dog
|Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. In Drosophila, the roundabout gene, a member of the immunoglobulin gene superfamily, encodes an integral membrane protein that is both an axon guidance receptor and a cell adhesion receptor. This receptor is involved in the decision by axons to cross the central nervous system midline. The protein encoded by this gene is structurally similar to the Drosophila roundabout protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. |
|Druggable Genome Axon guidance|
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TA303077 (1µg/ml) staining of HUVEC lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.