Home Antibody All anti-SLC6A4 antibodies
Also for SLC6A4 (NM_001045)
| Peptide with sequence C-LHQGERETWGK, from the internal region of the protein sequence according to NP_001036.1.|
|Test: Human, Rat. Expected from seq similarity: Human, Mouse, Rat
||ELISA: 1:32,000. WB: 1-3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 4 (SLC6A4)|
|5-HTT; 5-HTTLPR; 5HTT; hSERT; HTT; OCD1; SERT; SERT1|
Entrez Gene 6532 Human
Entrez Gene 15567 Mouse
Entrez Gene 25553 Rat
|This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq]. |
|TransmembraneDruggable Genome |
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TA303021 staining (1µg/ml) of Human Duodenum lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.