Home Antibody All anti-SRD5A2 antibodies
Also for SRD5A2 (NM_000348)
| Peptide with sequence QVQCQQSPVLAG, from the N Terminus of the protein sequence according to NP_000339.|
|Test: Human. Expected from seq similarity: Human
||ELISA: 1:16,000. WB: 0.3-1.0 µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (SRD5A2)|
Entrez Gene 6716 Human
|This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq]. |
|TransmembraneDruggable Genome Androgen and estrogen metabolismProstate cancer|
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TA302992 (0.3µg/ml) staining of human testes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.