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Home Antibody All anti-AKR1C3 antibodies

Anti-AKR1C3 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA302991 Goat Polyclonal Antibody against AKR1C3 100ug $325 3-7 Days
LC418464 AKR1C3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for AKR1C3 (NM_003739)
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OriGene Data

Immunogen Peptide with sequence CFASHPNYPYSDEY, from the C Terminus of the protein sequence according to NP_003730.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:32,000. WB: 0.01-0.1µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens aldo-keto reductase family 1, member C3 (AKR1C3), transcript variant 1
Alternative NameDD3; DDX; HA1753; HAKRB; HAKRe; hluPGFS; HSD17B5; PGFS
Database LinkNP_003730
Entrez Gene 8644 Human
FunctionThis gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq].
Related PathwayDruggable Genome Arachidonic acid metabolismMetabolism of xenobiotics by cytochrome P450

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA302991 (0.03µg/ml) staining of human breast lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


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