Home Antibody All anti-RGS1 antibodies
Also for RGS1 (NM_002922)
| Peptide with sequence C-NLLNDLQANSLK, from the C Terminus of the protein sequence according to NP_002913.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens regulator of G-protein signaling 1 (RGS1)|
|1R20; BL34; HEL-S-87; IER1; IR20|
Entrez Gene 5996 Human
Entrez Gene 50778 Mouse
Entrez Gene 54289 Rat
Entrez Gene 488585 Dog
|This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq]. |
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TA302787 staining (1µg/ml) of HepG2 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.