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Home Antibody All anti-CTTN antibodies

Anti-CTTN Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA302747 Goat Polyclonal Antibody against CTTN 100ug $325 3-7 Days
LC429248 CTTN HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

Immunogen Peptide with sequence WKASAGHAVSIA-C, from the N Terminus of the protein sequence according to NP_005222.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Mouse. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-2µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens cortactin (CTTN), transcript variant 1
Alternative NameEMS1
Database LinkNP_005222
Entrez Gene 2017 Human
Entrez Gene 13043 Mouse
Entrez Gene 60465 Rat
Entrez Gene 610283 Dog
FunctionThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq].
Related PathwayDruggable Genome Tight junctionPathogenic Escherichia coli infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302747 staining (0.5µg/ml) of A431 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.


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