Home Antibody All anti-SMAD4 antibodies
Also for SMAD4 (NM_008540)
| Peptide with sequence C-HTMPIADPQPLD, from the C Terminus of the protein sequence according to NP_005350.1.|
|Test: Mouse. Expected from seq similarity: Human, Mouse, Rat, Dog, PigCow
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Mus musculus SMAD family member 4 (Smad4)|
|AW743858; D18Wsu70e; DPC4; Madh4|
Entrez Gene 4089 Human
Entrez Gene 17128 Mouse
Entrez Gene 50554 Rat
Entrez Gene 476196 Dog
|Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily; SMAD4 is the common SMAD (co-SMAD). Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. May act as a tumor suppressor|
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TA302724 staining (0.5µg/ml) of NIH-3T3 cell lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.