Home Antibody All anti-UBE2L3 antibodies
Also for UBE2L3 (NM_003347)
| Peptide with sequence C-EFTKKYGEKRPVD, from the C Terminus of the protein sequence according to NP_003338.|
|Test: Human, Mouse, Rat. Expected from seq similarity: Human, Mouse, Cow
||ELISA: 1:128,000. WB: 0.5-2µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 1|
|E2-F1; L-UBC; UBCH7; UbcM4|
Entrez Gene 7332 Human
Entrez Gene 22195 Mouse
Entrez Gene 363836 Rat
|The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]. |
| Ubiquitin mediated proteolysisParkinson's disease|
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TA302697 staining (0.5µg/ml) of Hela lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.