Home Antibody All anti-IRAK4 antibodies
Also for IRAK4 (NM_016123)
| Peptide with sequence NKPITPSTYVRC, from the N Terminus of the protein sequence according to NP_057207.1.|
|Test: Human, Mouse. Expected from seq similarity: Human, Mouse
||ELISA: 1:32,000. WB: 1-3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2|
|IPD1; IRAK-4; NY-REN-64; REN64|
|This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [supplied by RefSeq]. |
Toll-like receptor signaling pathway
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TA302664 (1µg/ml) staining of Hela lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.