Home Antibody All anti-PIR antibodies
|Peptide with sequence GSSKKVTLSVLSREC, from the N Terminus of the protein sequence according to NP_003653.|
|Test: Human. Expected from seq similarity: Human, Mouse
||ELISA: 1:128,000. WB: 0.3 - 1.0 µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens pirin (iron-binding nuclear protein) (PIR), transcript variant 1|
|OTTHUMP00000022961; OTTHUMP00000022962; pirin; pirin (iron-binding nuclear protein)|
Entrez Gene 8544 Human
Entrez Gene 69656 Mouse
|This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described. |
|Transcription Factors |
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TA302574 (0.3µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.