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Home Antibody All anti-FH antibodies

Anti-FH Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302493
  • Goat Polyclonal Antibody against Fumarase / FH
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400053) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for FH (NM_000143)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-HPNDHVNKSQSSND, from the internal region of the protein sequence according to NP_000134.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Dog Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:64,000. WB: 0.01-0.03µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens fumarate hydratase (FH)
Alternative NameHLRCC; LRCC; MCL; MCUL1
Database LinkNP_000134
Entrez Gene 2271 Human
Entrez Gene 14193 Mouse
Entrez Gene 24368 Rat
Entrez Gene 480092 Dog
FunctionThe protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq].
Related PathwayDruggable Genome Citrate cycle (TCA cycle)Metabolic pathwaysPathways in cancerRenal cell carcinoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302493 (0.01µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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