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Home Antibody All anti-TRPM8 antibodies

Anti-TRPM8 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302225
  • Rabbit Polyclonal Antibody against TRPM8 (Center R536)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402977) , 20ug
100ug 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenThis antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the Center(R536) of human TRPM8.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:50~100; IHC: 1: 10~50; ELISA: 1: 1,000;
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens transient receptor potential cation channel, subfamily M, member 8 (TRPM8)
Alternative NameLTRPC6; TRPP8
Database LinkNP_076985
FunctionTRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. It is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. It is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.
Related Pathway

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WB Image
Western blot analysis of TRPM8 (arrow) using rabbit polyclonal TRPM8 Antibody (Center R536).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TRPM8 gene (Lane 2) (Origene Technologies).
IHC Image
Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with TRPM8 antibody (Center R536) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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