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Anti-PDK2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA302110 Rabbit Polyclonal Antibody against PDK2 (C-term) 100ug $325 2 Weeks
LC400923 PDK2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenThis PDK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-407 amino acids from the C-terminal region of human PDK2.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman, Mouse, Rat, Monkey Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000, IHC: 1:50~100
Predicted MW Explanation 46153 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reference Data

Target Namepyruvate dehydrogenase kinase 2
Alternative NamePDHK2|PDKII
Database LinkNP_002602
Entrez Gene 5164 Human
Entrez Gene 18604 Mouse
Entrez Gene 81530 Rat
Entrez Gene 704169 Monkey
FunctionPDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of PDK2 Antibody (C-term)(Cat. #TA302110) in mouse intestine tissue lysate (35ug/lane). PDK2 (arrow) was detected using the purified Pab.

WB Image
Western blot analysis of PDK2 (arrow) using PDK2 Antibody (C-term)(Cat. #TA302110). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDK2 gene (Lane 2) (Origene Technologies).

WB Image
PDK2 Antibody (C392) (Cat. #TA302110) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PDK2 antibody detected the PDK2 protein (arrow).

IHC Image
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.


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