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Home Antibody All anti-ALDH2 antibodies

Anti-ALDH2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302017
  • Rabbit Polyclonal Antibody against ALDH2 (N-term)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400231) , 20ug
100ug $325 3-7 Days
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WB(1)
IHC(1)
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Also for ALDH2 (NM_000690)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ALDH2.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:50~100; IHC: 1: 10~50; ELISA: 1: 1,000;
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), transcript variant 1
Alternative NameALDH-E2; ALDHI; ALDM
Database LinkNP_000681
FunctionALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.
Related Pathway

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WB Image
Western blot analysis of ALDH2 (arrow) using rabbit polyclonal ALDH2 Antibody (N-term) 56381 Da . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ALDH2 gene (Lane 2) (Origene Technologies).
IHC Image
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH2 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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