Home Antibody All anti-ROBO4 antibodies
Also for ROBO4 (NM_019055)
|A synthetic peptide made to a C-terminal region of the human protein (within residues 900-1007). [Swiss-Prot# Q8WZ75]|
|WB, IHC, IF
|Tris-citrate/phosphate [pH 7-8] and 0.1% sodium azide|
|Immunogen affinity purified
|Homo sapiens roundabout, axon guidance receptor, homolog 4 (Drosophila) (ROBO4), transcript variant 1|
Entrez Gene 54538 Human
|Roundabouts (ROBO) are cell-surface receptors that mediate repulsive signaling mechanisms at the central nervous system midline. However, ROBOs may also mediate attraction mechanisms in the context of vascular development. ROBO4 is a novel roundabout protein which is restricted in expression to endothelial cells in vitro and sites of angiogenesis in vivo. Because it is not expressed on normal endothelial cells, in vivo, it is a promising tumor endothelial marker.|
|Druggable Genome |
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Detection of ROBO4 in HUVEC lysate
Detection of ROBO4 in endothelium and trophoblasts of the placenta
Immunocytochemistry/Immunofluorescence: Robo4 antibody was tested in Huvec cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).