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Home Antibody All anti-BMI1 antibodies

Anti-BMI1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA301482 Rabbit Polyclonal Antibody against Bmi1 100ul $325 In Stock
LC401584 BMI1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide made to an internal region (within residues 1-100) of the human Bmi1 protein. [Swiss-Prot# P35226]
Clone Name IsotypeIgG
Species Reactivityhuman, mouse Concentration1.09 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB: 0.5-2 ug/ml
BufferTris-glycine, 150mM NaCl and 0.05% sodium azide
Purification Immunogen affinity purified

Reference Data

Target NameHomo sapiens BMI1 proto-oncogene, polycomb ring finger (BMI1)
Alternative NameFLVI2/BMI1; PCGF4; RNF51
Database LinkNP_005171
Entrez Gene 648 Human
Entrez Gene 12151 Mouse
FunctionThe Bmi1 oncogene has been shown to induce telomerase activity and immortalize human mammary epithelial cells. Bmi1 extends the replicative life span of human fibroblasts by suppressing the p16-dependent senescence pathway. Bmi1 is also important in maintaining stem cells' ability to self renew. It has also been termed an oncogene with aberrant expression in various carcinomas. It has been shown to be a negative regulator of p19Arf, Ink4a (p14Arf) and tp53 known tumor repressors. Ablation of Bmi1 is required for short term survival of cancer cells.
Related PathwayES Cell Differentiation/IPSTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Detection of Bmi1 protein in skeletal muscle
Immunocytochemistry/Immunofluorescence: BMI1 antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).


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