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Home Antibody All anti-LRPAP1 antibodies

Anti-LRPAP1 Antibody EPR3327

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301347
  • Rabbit Monoclonal Antibody against LRPAP1 (Clone EPR3327)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419397) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for LRPAP1 (NM_002337)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human LRPAP1 was used as an immunogen.
Clone NameEPR3327 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500~2000; IHC: 1: 100~250; FC: 1:20
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens low density lipoprotein receptor-related protein associated protein 1 (LRPAP1), transcript variant 1
Alternative NameA2MRAP; A2RAP; alpha-2-MRAP; HBP44; MRAP; MYP23; RAP
Database LinkNP_002328
FunctionThe low density lipoprotein receptor-related protein-associated protein 1 (LRPAP1/RAP) is an antagonist and molecular chaperone protein that binds tightly to low-density lipoprotein receptor family members and thereby prevents the binding of all known ligands, including alpha 2-macroglobulin and chylomicron remnants. LRPAP1 is present on the cell surface where it is an effective inhibitor of ligand binding to the kidney glycoprotein 330 (gp330), but is most abundant in the endoplasmic reticulum lumen and may function in receptor folding and/or trafficking (1-3).
Related Pathway

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WB Image
Western blot - LRPAP1 antibody [EPR3327]; All lanes : Anti-LRPAP1 antibody [EPR3327] at 1/2000 dilution.Lane 1 : fetal kidney lysate .Lane 2 : mouse kidney lysate.Lane 3 : rat kidney lysate.Lane 4 : 293T cell lysate.Lysates/proteins at 10 µg per lane.Secondary.goat anti-rabbit HRP labeled IgG at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 45 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - LRPAP1 antibody [EPR3327]; Immunohistochemical analysis of paraffin-embedded human brain tissue using TA301347, at 1/100-1/250 dilution.

 

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