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Home Antibody All anti-C1QC antibodies

Anti-C1QC Antibody EPR2984Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301321
  • Rabbit Monoclonal Antibody against C1QC (Clone EPR2984Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403541) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for C1QC (NM_172369)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human C1q (subunit A) was used as an immunogen.
Clone NameEPR2984Y IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500 - 1:1000; IP: 1:10; IHC-P: 1:100 - 1:250; ICC: 1:250 - 1:500; FC: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens complement component 1, q subcomponent, C chain (C1QC), transcript variant 2
Alternative NameC1Q-C; C1QG
Database LinkNP_758957
FunctionThe complement component C1 is a protein complex that consists of six subunits of C1q. Each C1q subunit of the complex is known to bind to immune complexes, which often are deposited in basement membrane. C1q is a versatile recognition protein that triggers activation of the classical pathway of complement, where the first step involves the binding of the globular domain of Clq to the Fc regions of aggregated IgG or IgM. The C1q globular domain is a heterotrimer of the C-terminal halves of one A, one B, and one C chain, held together mainly by non-polar interactions, with a Ca2+ ion bound at the top. A modular organization has been suggested of the globular domain, consistent with the view that A, B, and C chains are functionally autonomous modules and have distinct and differential ligand-binding properties (1-3).
Related Pathway

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WB Image
Western blot - C1QC antibody [EPR2984Y]; Anti-C1QC antibody [EPR2984Y] at 1/1000 dilution + human plasma lysate at 10 µg.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 26 kDa.Observed band size : 26 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - C1QC antibody [EPR2984Y]; TA301321 at 1/100 dilution staining C1q in human liver by Immunohistochemistry, Paraffin-embedded tissue.

 

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