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Home Antibody All anti-HNRNPC antibodies

Anti-HNRNPC Antibody EP3034Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301275
  • Rabbit Monoclonal Antibody against HNRNPC (Clone EP3034Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401430) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for HNRNPC (NM_004500)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human hnRNP C1/C2 was used as an immunogen.
Clone NameEP3034Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:50000 - 1:100000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
Predicted MW Explanation 34 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens heterogeneous nuclear ribonucleoprotein C (C1/C2) (HNRNPC), transcript variant 2
Alternative NameC1; C2; HNRNP; HNRPC; SNRPC
Database LinkNP_004491
Entrez Gene 3183 Human
Entrez Gene 15381 Mouse
Entrez Gene 290046 Rat
FunctionHeterogeneous nuclear ribonucleoproteins (hnRNPs) are predominantly nuclear RNA-binding proteins that form complexes with RNA polymerase II transcripts. These proteins function in a variety of cellular activities, ranging from transcription and pre-mRNA processing in the nucleus to cytoplasmic mRNA translation and turnover (1). hnRNP C1/C2 is one of the most abundant proteins in the nucleus, and shown to have roles in cellular differentiation and proliferation (2). A novel nuclear export is activated by the ROCK signaling pathway to exclude hnRNP C1/C2 from the nucleus, by which the compartmentalization of specific hnRNP components is disturbed in apoptotic cells (3). Overexpression of hnRNP C1/C2 in hepatocellular carcinoma (HCC) tissues has been reported in 70 HCC samples, suggesting its potential as a protein tumor marker (4).
Related Pathway Spliceosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - hnRNP C1 + C2 antibody [EP3034Y]; All lanes : Anti-hnRNP C1 + C2 antibody [EP3034Y] at 1/100000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : 293T cell lysate.Lane 3 : MCF7 cell lysate.Lane 4 : human cerebellum lysate.Lysates/proteins at 10 ug per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 34 kDa.Observed band size : 34 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - hnRNP C1 + C2 antibody [EP3034Y]; TA301275 at 1/100 dilution staining hnRNP C1 + C2 in human breast carcinoma by Immunohistochemistry, Paraffin-embedded tissue.

 

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