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Home Antibody All anti-AMPH antibodies

Anti-AMPH Antibody EP2061Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301217
  • Rabbit Monoclonal Antibody against AMPH (Clone EP2061Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400614) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for AMPH (NM_001635)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near C-terminus of human Amphipysin was used as an immunogen.
Clone NameEP2061Y IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:20000 - 1:100000; IP: 1:20; IHC-P: 1:100 - 1:250; ICC: 1:250 - 1:500; FC: 1:160
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens amphiphysin (AMPH), transcript variant 1
Alternative NameAMPH1
Database LinkNP_001626
FunctionAmphiphysin, a neuronal protein first identified in chicken synaptic membranes, is the autoantigen of Stiff-Man Syndrome (SMS) associated with breast cancer. Patient autoantibodies have a distinct pattern of reactivity with amphiphysin, and the dominant autoepitope is located in its C-terminal region, which contains an SH3 domain (1). Amphiphysin is expressed in many neurons, certain endocrine cell types, and spermatocytes (2). study suggests a link between amphiphysin I expression in cancer and amphiphysin I autoimmunity. The enhanced expression of amphiphysin I in some forms of cancer supports the hypothesis that amphiphysin family members may play a role in the biology of cancer cells (3).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Amphiphysin antibody [EP2061Y]; All lanes : Anti-Amphiphysin antibody [EP2061Y] at 1/100000 dilution.Lane 1 : Human brain tissue lysate.Lane 2 : Mouse brain tissue lysate.Lane 3 : Rat brain tissue lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 76 kDa.Observed band size : 128 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Amphiphysin antibody [EP2061Y]; TA301217 at 1/100 dilution, staining Amphiphysin in human brain by Immunohistochemistry using paraffin-embedded tissue.

 

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