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Home All anti-DAB2 antibodies

Anti-DAB2 Antibody EP2297Y

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA301090
  • Rabbit Monoclonal Antibody against DAB2 (Clone EP2297Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400534) , 20ug
100µl $325 In Stock Add to Shopping Cart
WB(1)
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Also for DAB2 (NM_001343)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) (DAB2), transcript variant 1
Synonyms:DOC-2; DOC2
ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human Dab2 was used as an immunogen.
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Clone NameEP2297Y IsotypeIgG
Species ReactivityHuman Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:2,000; ICC: 1: 100; FC: 1:50; IP: 1:20
BackgroundDab2 (Disabled homolog 2, Diabled-2) is a mammalian structural homolog of Drosophila Disabled protein and a mitogen-responsive phosphoprotein (1). As a component of the CSF1 signal transduction pathway, Dab2 is normally expressed in ovarian epithelia cells. However, in ovarian carcinoma, Dab2 expression is either lost or down-regulated. Therefore, Dab2 is speculated to be a negative regulator of growth and its down-regulation considered to play critical role in ovarian carcinogenesis (2).
Related Pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway

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WB Image
Western blot analysis on human pancreas tissue lysates using anti-Dab2, 1:2000 dilution.

 

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