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Anti-KITLG Antibody EP665Y
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Also for KITLG (NM_000899)
|A synthetic peptide corresponding to residues near the N-terminus of human SCF was used as an immungen.|
||WB: 1: 10,000; IHC: 1: 100 250; ICC: 1: 100 250; FC: 1:90
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens KIT ligand (KITLG), transcript variant b|
|FPH2; Kitl; KL-1; MGF; SCF; SF; SHEP7|
|Novel hematopoietic growth factor, stem cell factor (SCF), was cloned and demonstrated to be the ligand for the c-kit tyrosine kinase receptor. SCF is encoded by Sl (steel), a gene critical to the development of several distinct cell lineages during embryonic life and which has important effects on hematopoiesis in the adult (1). SCF is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow cultures. SCF exhibits potent synergistic activities in conjunction with colony-stimulating factors, resulting in increased colony numbers and colony size (2). |
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
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Western blot analysis on 5ng of recombinant protein using SCF, dilution 1:10,000.
Immunohistochemical analysis of paraffin-embedded human klidney carcinoma using anti-SCF.