OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-TUBB3 antibodies

Anti-TUBB3 Antibody EP1569Y

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA300866
  • Rabbit Monoclonal Antibody against TUBB3 (Clone EP1569Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416872) , 20ug Explanation
100ul $325 3-7 Days
Add to Shopping Cart
spacer
WB(1)
IHC(1)
spacer
Also for TUBB3 (NM_006086)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to the C-term of human class III ß-Tubulin was used as immunogen.
Clone NameEP1569Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:40; ICC: 1:100 - 1:250; FC: 1:10; IHC-P: 1:50 - 1:100
Predicted MW Explanation 55 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens tubulin, beta 3 class III (TUBB3), transcript variant 1
Alternative Namebeta-4; CDCBM; CDCBM1; CFEOM3; CFEOM3A; FEOM3; TUBB4
Database LinkNP_006077
Entrez Gene 10381 Human
Entrez Gene 22152 Mouse
Entrez Gene 246118 Rat
FunctionMicrotubules are essential parts in eukaryotic cell structures, transportation, and mitosis and consists mainly of 2 soluble protein subunits, alpha and beta tubulin. Beta-tubulin binds to alpha tubulin to form tubulin heterodimer which is post-translationally modified (1). The tubulin dimer complex binds to GTP and assembles onto the positive ends of microtubules. After incorporation into the microtubules, bound GTP is hydrolyzed by beta tubulin. The stability of the dimer in the microtubules is depended on presence of beta tubulin, where dimer with GTP bound beta-tubulin is stable to microtubule incorporation (2). Class III beta tubulin (beta III-tubulin) is a vertebrate tubulin Isotype specific to the neurons and mammalian testis cells, making it an ideal neuronal marker. Overexpression of class III beta tubulin is associated with the resistances of microtubule-targeted cancer drugs in lung cancer cell lines, breast cancer cell lines, and ovarian tumors (3).
Related PathwayES Cell Differentiation/IPSDruggable Genome Gap junctionPathogenic Escherichia coli infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-beta III Tubulin antibody [EP1569Y]; Anti-beta III Tubulin antibody [EP1569Y] at 1/10000 dilution + HeLa cell lysate at 10 ug.Secondary.goat anti-rabbit HRP at 1/2000 dilution
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - beta Tubulin antibody [EP1569Y]; TA300866, at a 1/50 dilution, staining human class III beta Tubulin in breast carcinoma tissue using Immunohistochemistry, Paraffin embedded tissue.

 

spacer
Inc 5000 Healthcare Company Copyright © 2015 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title