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Home All anti-TNF antibodies

Anti-TNF Antibody EP1085Y

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA300746
  • Rabbit Monoclonal Antibody against TNF (Clone EP1085Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424626) , 20ug
100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
30ul
$100
$50*
In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
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Also for TNF (NM_000594)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to the extracellular portion of human TNF-a was used as immunogen.
Clone NameEP1085Y IsotypeIgG
Species ReactivityHuman Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:500
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Reference Data

Target NameHomo sapiens tumor necrosis factor (TNF)
Alternative NameDIF; TNF-alpha; TNFA; TNFSF2
Database LinkNP_000585
FunctionTumor necrosis factor is a multifunctional proinflammatory cytokine, with effects on lipid metabolism, coagulation, insulin resistance, and endothelial function. Tumor necrosis factor-alpha (TNF-?), the product of activated monocytes, is secreted by macrophages in response to inflammation, infection and cancer (1). TNF-? triggers a signaling cascade, converging on the activation of the transcription factor NF-kappa B, which forms the basis for numerous physiological and pathological processes (2). TNF-? has been shown to play a role in systems such as the pathogenesis of psoriasis, tuberculosis, obesity, cerebral malaria, rheumatoid arthritis and asthma (3).
Related Pathway
Adipogenesis
Apoptosis
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
MAPK signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis using anti-TNF-α, dilution 1:500.

 

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