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Home Antibody All anti-AFP antibodies

Anti-AFP Antibody EP1016Y

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SKU Description Amount Price Availability*  
TA300729
  • Rabbit Monoclonal Antibody against AFP (Clone EP1016Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400455) , 20ug Explanation
100ul 325 In Stock
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WB(1)
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Also for AFP (NM_001134)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-term of human AFP was used as an immunogen.
Clone NameEP1016Y IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500000; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-Fr or IHC-P.

Reference Data

Target NameHomo sapiens alpha-fetoprotein (AFP)
Alternative NameFETA; HPAFP
Database LinkNP_001125
FunctionAlpha-fetoprotein (AFP) is a serum glycoprotein protein produced in the liver or yolk sac of fetal staged mammals. AFP synthesis is minimal after birth and trace amount is expressed in the adult liver (1). AFP gene expression is regulated by the interactions between steroid hormone receptors and transcriptional factors in separate signal transduction pathways (2). AFP functions as a binding and transporting ligand and cell growth regulator. Elevated expression level of AFP has been implicated in colorectal, ovarian, pancreatic, testicular, and certain liver cancers. High levels of AFP are also seen in some diseases such as hepatitis and colitis. AFP is used as a screening marker for fetal abnormalities in pregnant women such as Down syndrome. Recently, AFP has been introduced as an anti-cancer drugs-ligand carrier, transporting drugs to target tumor cells, increasing anti-tumor efficiency (3).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - alpha 1 Fetoprotein antibody [EP1016Y]; Anti-alpha 1 Fetoprotein [EP1016Y] antibody at 1/500000 dilution + HepG2 cell lysate at 10 ug.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 69 kDa.Observed band size : 69 kDa.

 

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