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Anti-MUC1 Antibody EP1024Y

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues near the N-terminus of human MUC1 was used as an immunogen.
Clone Name	EP1024Y	Isotype	IgG
Species Reactivity	Human, Mouse, Rat	Concentration
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1: 1000; IHC: 1: 100 250; FC: 1:30; IP: 1:50
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens mucin 1, cell surface associated (MUC1), transcript variant 1
Alternative Name	CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; PEM; PEMT; PUM
Database Link	NP_002447
Function	Mucins are high molecular weight glycoproteins that provide a protective layer on epithelial surfaces and are involved in cell-cell interactions, signaling, and metastasis. MUC1 consists of an extracellular subunit and a membrane-associated subunit (1). The two moieties are produced from a single precursor polypeptide by an early proteolytic cleavage event but remain associated throughout intracellular processing and transport to the cell surface. It has been shown that MUC1 expression inhibits erbB1 (regulators of cell survival and growth) degradation and also E-cadherin (2). Isoform 7 of MUC1 behaves as a receptor and binds the secreted isoform 5. The binding induces the phosphorylation of the isoform 7, alters cellular morphology and initiates cell signaling (3).
Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of mucin 1, cell surface associated (MUC1), transcript variant 1 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • MUC1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • MUC1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Muc1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • MUC1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Muc1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens mucin 1, cell surface associated (MUC1), transcript variant 1 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens mucin 1, cell surface associated (MUC1), transcript variant 1 as transfection-ready DNA • Lenti ORF clone of Human mucin 1, cell surface associated (MUC1), transcript variant 1 , Myc-DDK-tagged • Lenti ORF clone of Human mucin 1, cell surface associated (MUC1), transcript variant 1, mGFP tagged • Myc-DDK-tagged ORF clone of Homo sapiens mucin 1, cell surface associated (MUC1), transcript variant 1 as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens mucin 1, cell surface associated (MUC1), transcript variant 1 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)