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Anti-APCS Antibody EP1018Y

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues near the N-term of human SAP was used as an immunogen.
Clone Name	EP1018Y	Isotype	IgG
Species Reactivity	Human	Concentration
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1: 1,000,000; IHC: 1: 100~250
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens amyloid P component, serum (APCS)
Alternative Name	PTX2; SAP
Database Link	NP_001630
Function	Serum Amyloid P (SAP) is a non-fibrillar plasma glycoprotein that belongs to the pentraxin family. It is universally found in amyloid deposits and this is probably due to its specific calcium-dependent binding to motifs present on all types of amyloid fibrils. SAP is also found to prevent fibrillar breakdown by enzymes and it is believed that it helps maintains stability of the amyloid deposits (1,2). It has been shown that SAP binds monocytes with high avidity, but does not bind to erythrocytes, NK cells, T lymphocytes or B lymphocytes (3). SAP production can be induced by exposure to IL-1, IL-6 and IFN-beta. The SAP-inducing activity was neutralized by antibodies to each of the recombinant cytokines (4).
Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of amyloid P component, serum (APCS) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • APCS - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • APCS - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Apcs - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • APCS - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Apcs - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens amyloid P component, serum (APCS) as transfection-ready DNA • Lenti ORF clone of Human amyloid P component, serum (APCS) , Myc-DDK-tagged • Lenti ORF clone of Human amyloid P component, serum (APCS), mGFP tagged • GFP-tagged ORF clone of Homo sapiens amyloid P component, serum (APCS) as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens amyloid P component, serum (APCS) as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens amyloid P component, serum (APCS) as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)