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Home Antibody All anti-HSPD1 antibodies

Anti-HSPD1 Antibody EP1006Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300692
  • Rabbit Monoclonal Antibody against HSPD1 (Clone EP1006Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400783) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for HSPD1 (NM_002156)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the internal region of human Hsp60 was used as an immunogen.
Clone NameEP1006Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:5000; IHC: 1: 100-250
Predicted MW Explanation 60 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), transcript variant 1
Alternative NameCPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13
Database LinkNP_002147
Entrez Gene 3329 Human
Entrez Gene 15510 Mouse
Entrez Gene 63868 Rat
FunctionThe 60-kDa Heat Shock Protein (Hsp60) is a highly conserved member of the molecular chaperone network commonly imported into the mitochondria to assist in the folding and assembly of mitochondrial proteins (1). Under environmental stress conditions, synthesis of Hsp60 is up-regulated then involved in gene expression regulation, DNA replication, signal transduction, differentiation, apoptosis, cellular senescence or immortalization (2). Hsp60 is also believed to protect mitochondrial ATPase activity under conditions of increasing temperature (3). Hsp60, along with Hsp70, has also been shown to play a role in a danger signalling cascade in response to bacterial infection (4).
Related PathwayStem cell - PluripotencyDruggable Genome RNA degradationType I diabetes mellitus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Hsp60 antibody [EP1006Y]; Anti-Hsp60 antibody [EP1006Y] at 1/5000 dilution + T47D cell lysate at 10 ug.Secondary.Goat anti-Rabbit HRP labelled, at 1/2000 dilution.Predicted band size : 60 kDa.Observed band size : 60 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Hsp60 antibody [EP1006Y]; Ab45134 at 1/100 staining human Hsp60 in human breast carcinoma by immunohistochemistry using paraffin embedded tissue.

 

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