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Anti-HSPD1 Antibody EP1006Y

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues in the internal region of human Hsp60 was used as an immunogen.
Clone Name	EP1006Y	Isotype	IgG
Species Reactivity	Human, Mouse, Rat	Concentration
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:5000; IHC: 1: 100-250
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1
Alternative Name	CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13
Database Link	NP_002147
Function	The 60-kDa Heat Shock Protein (Hsp60) is a highly conserved member of the molecular chaperone network commonly imported into the mitochondria to assist in the folding and assembly of mitochondrial proteins (1). Under environmental stress conditions, synthesis of Hsp60 is up-regulated then involved in gene expression regulation, DNA replication, signal transduction, differentiation, apoptosis, cellular senescence or immortalization (2). Hsp60 is also believed to protect mitochondrial ATPase activity under conditions of increasing temperature (3). Hsp60, along with Hsp70, has also been shown to play a role in a danger signalling cascade in response to bacterial infection (4).
Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • HSPD1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • HSPD1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Hspd1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • HSPD1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Hspd1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 as transfection-ready DNA • Lenti ORF clone of Human heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 , Myc-DDK-tagged • Lenti ORF clone of Human heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged • GFP-tagged ORF clone of Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)