OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-RHOA antibodies

Anti-RHOA Antibody EP487Y

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA300589 Rabbit Monoclonal Antibody against RHOA (Clone EP487Y) 100ul $325 In Stock
LC400630 RHOA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
Add to Shopping Cart

spacer
WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-term of human Rho was used as immunogen. The antibody is predicted to detect RhoA, RhoB and RhoC based on sequence analysis.
Clone NameEP487Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:2,000-10,000; IHC: 1: 100-250; ICC: 1:250-500; IP: 1:50
Predicted MW Explanation 21 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens ras homolog family member A (RHOA)
Alternative NameARH12; ARHA; RHO12; RHOH12
Database LinkNP_001655
Entrez Gene 387 Human
Entrez Gene 11848 Mouse
Entrez Gene 117273 Rat
FunctionRho belongs to the Ras super family of low molecular weight GTPases. Fifteen Rho proteins have already been characterized and divided into three sub-families; the first includes Rho (A, B, C), the second, Rnd 1-3 and the third which includes Rac 1-3, RhoG, Cdc42Hs, Rho/TTF. TC10 and Chp (1-2). Rho acts as a molecular switch which turns on of off various intracellular signaling pathways such as ACK, PAKs, MEKKs ROCK (3). Rho is active when bound to GTP and inactive when bound to GDP (4). It is also known to participate in many physiological activities including cell migration, adhesion, cytokinesis, proliferation, differentiation and apoptosis and to a greater extend cell transformation (5).
Related PathwayDruggable Genome Chemokine signaling pathwayVascular smooth muscle contractionWnt signaling pathwayTGF-beta signaling pathwayAxon guidanceFocal adhesionMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Rho antibody [EP487Y]; Anti-Rho antibody [EP487Y] + 10ug HL60 cell lysate.Predicted band size : 21 kDa.Observed band size : 22 kDa .
spacer
Immunohistochemistry (Paraffin-embedded sections) - Rho antibody [EP487Y]; TA300589 at a 1:100 dilution staining Rho in human prostate carcinoma tissue.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title