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Home Antibody All anti-MALT1 antibodies

Anti-MALT1 Antibody EP603Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300586
  • Rabbit Monoclonal Antibody against MALT1 (Clone EP603Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402030) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for MALT1 (NM_006785)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the N-term of human MALT1 was used as immunogen. This antibody is predicted to detect splice isoform 2 based on sequence analysis.
Clone NameEP603Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:30
BufferDoes not react with Mouse, Rat. Is unsuitable for IHC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IHC or IP.

Reference Data

Target NameHomo sapiens mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 1
Alternative NameIMD12; MLT; MLT1
Database LinkNP_006776
FunctionMucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), also known as MLT1 or paracaspase 1, is a member of the human paracaspase family and an interacting partner of B-cell lymphoma 10 (Bcl-10) (1). In vitro, In vitro, MALT1 synergizes with BCL10 to enhance nuclear factor B activation (2) and to mediate IB kinase (IKK) activation by facilitating the ubiquitinylation of the NF-B essential modulator (NEMO) (3). MALT1 is found in recurrent chromosomal translocations in non-Hodgkin B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT). One common translocation juxtaposes the MALT1 gene to the IgH promoter region, resulting in up-regulation of Bcl-10 and MALT1 (4). Another common translocation creates a fusion between MALT1 and the inhibitor of apoptosis gene API2 ( cIAP2/HIAP1) (5).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - MALT1 antibody [EP603Y]; Anti-MALT1 antibody [EP603Y] at 1/2000 dilution + Jurkat cell lysate.Predicted band size : 92 kDa.Observed band size : 92 kDa.

 

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