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Home Antibody All anti-HDAC3 antibodies

Anti-HDAC3 Antibody Y415

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300508
  • Rabbit Monoclonal Antibody against HDAC3 (Clone Y415)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401280) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for HDAC3 (NM_003883)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the C-term of human Histone deacetylase 3 was used as immunogen. This antibody may detect splice isoform 2 (RPD3-2A) according to sequence analysis.
Clone NameY415 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:5,000-10,000; IHC: 1:250-500; ICC: 1:250-500; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Protein A purified

Reference Data

Target NameHomo sapiens histone deacetylase 3 (HDAC3)
Alternative NameHD3; RPD3; RPD3-2
Database LinkNP_003874
FunctionHistone deacetylase 3 belongs to the histone deacetylase family type 1 which actively deacetylate Histones. Currently 3 known isoforms exists (HDAC3, HDAC3A and HDAC3C) (1). HDAC3 represses transcription and binds transcription factor YY1 to form a large complex. N-Cor binds HDAC3 in a different manner than other HDACs. In addition to N-Cor, HDAC3 will form a complex with corepressor SMRT (2). HDAC3 is also known to interact with DAXX, HDAC10 and DACH1.
Related Pathway

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WB Image
Western blot - HDAC3 antibody [Y415]; Anti-HDAC3 antibody [Y415] at 1/10000 dilution + K562 cell lysate.Predicted band size : 49 kDa.Observed band size : 49 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - HDAC3 antibody [Y415]; Paraffin-embedded human ovary carcinoma.TA300508 at 1/250 dilution
IF Image
Immunocytochemistry/ Immunofluorescence - HDAC3 antibody [Y415]; Immunofluorescent staining of HeLa cells.using TA300508 at 1/250 dilution

 

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