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Home Antibody All anti-MAP2K1IP1 antibodies

Anti-MAP2K1IP1 Antibody Y130

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300464
  • Rabbit Monoclonal Antibody against MAP2K1IP1 (Clone Y130)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC411845) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(2)
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Also for MAP2K1IP1 (NM_021970)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the C-terminus of human mitogen-activated protein kinase kinase 1 interacting protein 1 was used as immunogen.
Clone NameY130 IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000; IHC: 1: 100-250; ICC: 1:50-100; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction
Note Does not react with Rat

Reference Data

Target NameHomo sapiens late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (LAMTOR3), transcript variant 1
Alternative NameMAP2K1IP1; MAPBP; MAPKSP1; MP1; PRO0633; Ragulator3
Database LinkNP_068805
Entrez Gene 8649 Human
Entrez Gene 56692 Mouse
FunctionThe function of MP1 (MEK partner-1) a 14kDa scaffold protein, is to bind specifically to MEK1 and ERK1 and bring them in close proximity in order to facilitate their activation (1). Localized to the late endosome, MP1 also interacts with an adaptor protein p14. While the interaction between MP1-ERK1 can take place in the absence of the adaptor protein p14, it is strengthened in the presence of p14 (2). Additionally, it has been suggested that the binding of MP1 to MEK1resides in a proline-rich sequence (residue 270-307) of MEK1
Related PathwayDruggable Genome MAPK signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - MAP2K1IP1 antibody [Y130]; Anti-MAP2K1IP1 antibody [Y130] at 1/50000 dilution + A431 cell lysate.Observed band size : 14 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - MAP2K1IP1 antibody [Y130]; TA300464, staining human breast carcinoma by immunohistochemistry, Paraffin embedded tissue
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAP2K1IP1 antibody [Y130]; TA300464 showing positive staining in Breast carcinoma tissue.

 

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