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Home Antibody All anti-SYP antibodies

Anti-SYP Antibody YE269

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300431
  • Rabbit Monoclonal Antibody against SYP (Clone YE269)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401102) , 20ug
100ul 325 In Stock
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WB(1)
IHC(3)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in C-terminus (cytoplasmic domain) of human Synaptophysin was used as immunogen. Predicted to cross-react with bovine, based on sequence homology.
Clone NameYE269 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:10000 - 1:50000; ICC/IF: 1:250; IHC-P: 1:250 - 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens synaptophysin (SYP)
Alternative NameMRX96; MRXSYP
Database LinkNP_003170
FunctionSynaptophysin (SypI), also referred as p38 (1), constitutSyp I contains four transmembrane regions and can be phosphorylated on its cytoplasmic C-terminus by both serine/threonine and tyrosine kinases (2). In addition to syp I, synaptic vesicles contain a highly homologous membrane protein named synaptoporin or synaptophysin II (Syp II) (3). While Syp I is ubiquitously expressed and present in virtually all synapses whereas Syp II is expressed at high levels only in selected neurons (4). es approximately 7% of the total vesicle protein and is selectively associated with small synaptic vesicles (SSVs)
Related Pathway

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WB Image
Western blot - Synaptophysin antibody [YE269]; Anti-Synaptophysin antibody [YE269] at 1/10000 dilution + PC12 cell lysate.Predicted band size : 34 kDa.Observed band size : 34 kDa.Additional bands at : 21 kDa,22 kDa. We are unsure as to the identity of these extra bands.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Synaptophysin antibody [YE269]; TA300431 showing positive staining in Medulloblastoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Synaptophysin antibody [YE269]; TA300431 showing positive staining in Lung neuroendocrine tumor tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Synaptophysin antibody [YE269]; TA300431 showing positive staining in normal pancreas tissue.
IF Image
Immunofluorescence - Synaptophysin antibody [YE269]; Ab32127, at a dilution of 1/250, staining Synaptophysin in PC12 cells by Immunofluorescence.

 

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