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Home Antibody All anti-GRIA1 antibodies

Anti-GRIA1 Antibody E308

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300402
  • Rabbit Monoclonal Antibody against GRIA1 (Clone E308)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400293) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(2)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near N-terminus of human Glutamate receptor 1 was used as immunogen. Predicted to cross-react with rat, based on sequence homology.
Clone NameE308 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000; IHC: 1:50; IP: 1:30
Predicted MW Explanation 101 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 1
Alternative NameGluA1; GLUH1; GLUR1; GLURA; HBGR1
Database LinkNP_000818
Entrez Gene 2890 Human
FunctionGlutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration (3).
Related PathwayTransmembraneIon Channels: Glutamate ReceptorsDruggable Genome Neuroactive ligand-receptor interactionLong-term potentiationLong-term depressionAmyotrophic lateral sclerosis (ALS)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Glutamate Receptor 1 (AMPA subtype) antibody [E308]; Anti-Glutamate Receptor 1 (AMPA subtype) antibody [E308] at 1/1000 dilution + SH-SY5Y cell lysate.Predicted band size : 101 kDa.Observed band size : 106 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Glutamate Receptor 1 (AMPA subtype) antibody [E308]; Ab32436, at a 1/50 dilution, staining Glutamate Receptor 1 (AMPA subtype) in paraffin embedded human brain tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Glutamate Receptor 1 (AMPA subtype) antibody [E308]; Immunohistochemical analysis of Human hippocampus tissue, staining Glutamate Receptor 1 (AMPA subtype) with TA300402. Antigen retrieval was performed by heat mediation in a citrate buffer (pH 6). Samples were blocked with 10% normal goat serum for 30 minutes before incubating with primary antibody (1/20) for 2 hours. A biotinylated anti-rabbit IgG was used as the secondary antibody and staining was detected using DAB.

 

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