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Anti-GRIA1 Antibody E308

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues near N-terminus of human Glutamate receptor 1 was used as immunogen. Predicted to cross-react with rat, based on sequence homology.
Clone Name	E308	Isotype	IgG
Species Reactivity	Human	Concentration
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1: 1000; IHC: 1:50; IP: 1:30
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 1
Alternative Name	GluA1; GLUH1; GLUR1; GLURA; HBGR1
Database Link	NP_000818
Function	Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration (3).
Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 1 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • GRIA1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • GRIA1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Gria1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • GRIA1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Gria1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 1 as transfection-ready DNA • Lenti ORF clone of Human glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 1 , Myc-DDK-tagged • Lenti ORF clone of Human glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 1, mGFP tagged • GFP-tagged ORF clone of Homo sapiens glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 1 as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 1 as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 1 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)