OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-ESR1 antibodies

Anti-ESR1 Antibody E91

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300369
  • Rabbit Monoclonal Antibody against ESR1 (Clone E91)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400046) , 20ug
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)
IHC(1)
IF(1)
spacer
Also for ESR1 (NM_000125)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic phospho-peptide corresponding to residues surrounding Ser118 of human ERalpha was used as immunogen. The antibody only detects ERalpha phosphorylated on Serine 118.
Clone NameE91 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1: 1,000; IHC: 1:50; ICC: 1:50-1: 100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens estrogen receptor 1 (ESR1), transcript variant 1
Alternative NameER; Era; ESR; ESRA; ESTRR; NR3A1
Database LinkNP_000116
FunctionEstrogen receptor alpha (ER alpha) is a nuclear protein and member of the steroid hormone receptor family. ER alpha possesses both DNA binding and ligand binding domains, and exerts a significant role in activating the transcription of certain genes (1). Ligand-dependent dimerization and phosphorylation on serines, 104, 106, and 118 function to regulate the transcriptional activation of ER alpha (2). The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER activation function 1 (AF-1) (3).
Related Pathway
TGF Beta Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Estrogen Receptor alpha (phospho S118) antibody [E91]; All lanes : Anti-Estrogen Receptor alpha (phospho S118) antibody [E91] at 1/1000 dilution.Lane 1 : MCF7 cell lysate (untreated).Lane 2 : MCF7 cell lysate (treated with b-Estradiol and EGF).Predicted band size : 66 kDa.Observed band size : 60 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Estrogen Receptor alpha (phospho S118) antibody [E91]; Immunohistochemical staining of (A) untreated and (B) Phosphatase-treated paraffin-embedded human breast adenocarcinoma using TA300369 at 1:50 dilution.
IF Image
Immunofluorescence - Estrogen Receptor alpha (phospho S118) antibody [E91]; Immunofluorescent staining of (A) untreated and (B) Phosphatase-treated MCF-7 cells using TA300369.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title