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Home All anti-ESR1 antibodies
Anti-ESR1 Antibody E91
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for ESR1 (NM_000125)
OriGene Data
| A synthetic phospho-peptide corresponding to residues surrounding Ser118 of human ERalpha was used as immunogen. The antibody only detects ERalpha phosphorylated on Serine 118. |
| E91 |
IgG |
| Human |
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| WB, IHC, IF |
WB: 1: 1,000; IHC: 1:50; ICC: 1:50-1: 100 |
| 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens estrogen receptor 1 (ESR1), transcript variant 1 |
| ER; Era; ESR; ESRA; NR3A1 |
| NP_000116 |
| Estrogen receptor alpha (ER alpha) is a nuclear protein and member of the steroid hormone receptor family. ER alpha possesses both DNA binding and ligand binding domains, and exerts a significant role in activating the transcription of certain genes (1). Ligand-dependent dimerization and phosphorylation on serines, 104, 106, and 118 function to regulate the transcriptional activation of ER alpha (2). The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER activation function 1 (AF-1) (3). |
TGF Beta Signaling Pathway |
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on MCF7 cell lysate using anti-Phospho-ER alpha (S118); dilution 1:1,000. Cell lysates were (1) untreated, or (2) treated with b-Estradiol and EGF.
IHC Image
Immunohistochemical staining of (A) untreated and (B) Phosphatase-treated paraffin-embedded human breast adenocarcinoma using anti-Phospho-ER alpha (S118).
IF Image
Immunofluorescent staining of (A) untreated and (B) Phosphatase-treated MCF-7 cells using anti-Phospho-ER alpha (S118)
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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