Home Antibody All anti-HS2ST1 antibodies
Also for HS2ST1 (NM_012262)
|This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human HS2ST1.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1: 10~50; IHC: 1:50~100; ELISA: 1: 1,000
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. Storage: (Protein A or G Sepharose)
|Homo sapiens heparan sulfate 2-O-sulfotransferase 1 (HS2ST1), transcript variant 1|
|Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. Heparan sulfate 2-O-sulfotransferase is a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of the HS2ST1 gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.|
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Western blot analysis of HS2ST1 (arrow) using rabbit polyclonal HS2ST1 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HS2ST1 gene (Lane 2)
Formalin-fixed and paraffin-embedded human brain tissue reacted with HS2ST1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.