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Home Antibody All anti-SYN1 antibodies

Anti-SYN1 PHOSPHO Antibody E377

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303710
  • Rabbit monoclonal antibody against Synapsin I Phospho (pS553)(E377) (phospho-specific)
100ul 325 3-7 Days
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WB(1)
IF(1)
DB(1)
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Also for SYN1 (NM_006950)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic phospho-peptide corresponding to residues surrounding Ser553 of human Synapsin was used as immunogen. The antibody only detects Synapsin phosphorylated on Serine 553.
Clone NameE377 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF, DB Suggested DilutionsWB: 1:10,000-50,000; ICC: 1:50-100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction

Reference Data

Target NameHomo sapiens synapsin I (SYN1), transcript variant Ia
Alternative NameSYN1a; SYN1b; SYNI
Database LinkNP_008881
FunctionThis gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].
Related Pathway

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WB Image
Western blot - Synapsin I (phospho S553) antibody [E377]; Anti-Synapsin I (phospho S553) antibody [E377] at 1/50000 dilution + mouse brain lysate.Predicted band size : 85 kDa.Observed band size : 74 kDa .
IF Image
Immunocytochemistry/ Immunofluorescence - Synapsin I (phospho S553) antibody [E377]; Immunofluorescent staining of PC-12 cells using TA303710 at a dilution of 1/50 -1/100
DB Image
Dot Blot - Synapsin I (phospho S553) antibody [E377]; Dot Blot analysis on immunogen phospho-peptide (A) and non-phospho peptide (B) using TA303710 at a dilution of 1/500

 

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