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Anti-STK11 PHOSPHO Antibody
Also for STK11 (NM_000455)
|The antiserum was produced against A synthesized peptide derived from human LKB1 around the phosphorylation site of Serine 428|
||WB: 1:500-1:2000; IHC: 1:50-1:200; IF/ICC: 1:100-1:500
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens serine/threonine kinase 11 (STK11)|
|hLKB1; LKB1; PJS|
|ubiquitously expressed kinase of the CAMKL family with a tumor suppressor activity. Phosphorylates AGS3 (activator of G-protein signaling 3) GPR domains, regulating the interaction of GPR-containing proteins with G-proteins. Strongest expression in testis and fetal liver. Mutations in LKB1 lead to the Peutz-Jeghers cancer syndrome.|
TGF Beta Signaling Pathway
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Western blot analysis of LKB1 phosphorylation expression in PMA treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.