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Home Antibody All anti-Stat5a antibodies

Anti-Stat5a TRUEMAB Antibody Clone OTI4H1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500006 Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1) 100ul $325 In Stock
LC418866 STAT5A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500006 Carrier-free (BSA/glycerol-free) Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1) 100ug $450 3-4 weeks
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WB(2)
IHC(13)
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Also for Stat5a (NM_003152)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 2-104 of human Stat5a (NP_003143) produced in E.coli.
Clone NameClone OTI4H1 IsotypeIgG1
Species ReactivityHuman, Rat Concentration0.5 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB 1:200~500, IHC 1:50,
Predicted MW Explanation 90.5 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens signal transducer and activator of transcription 5A (STAT5A), transcript variant 2
Alternative NameMGF; STAT5
Database LinkNP_003143
Entrez Gene 6776 Human
Entrez Gene 24918 Rat
FunctionStat5a is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
Related PathwayStem cell relevant signaling - DSL/Notch pathwayStem cell relevant signaling - JAK/STAT signaling pathwayES Cell Differentiation/IPSTranscription FactorsDruggable Genome ErbB signaling pathwayJak-STAT signaling pathwayPathways in cancerChronic myeloid leukemiaAcute myeloid leukemia

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-Stat5a monoclonal antibody.
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STAT5a antibody ( 4H1) at 1:500 dilution + lysate from 293T cells transfected with human Stat5a expression vector (Cat# RC205753)
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Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Human lung tissue within the normal limits using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Human thyroid tissue within the normal limits using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-Stat5a mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500006)
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