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Anti-STAT3 Antibody E121-31
Also for STAT3 (NM_213662)
|A synthetic phospho-peptide corresponding to residues surrounding Ser727 of human Stat3 was used as immunogen. The antibody detects Stat3 phosphorylated on Serine 727. It does not cross-react with the phospho-serines of other Stat proteins. Predicted to c|
||0.5~1.0 mg/ml (Lot Dependent)
||ICC/IF: 1:100; IP: 1:40; WB: 1:1000 - 1:10000; IHC-P: 1:50
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt.
|Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 3|
|Stat3 is a member of a group of proteins (Signal Transduction and Activators of Transcription) that act as both signal transducers for cytokines and growth factors, as well as transcription factors (1,2). Stats are activated by tyrosine phosphorylation in response to different ligands, after which they translocate to the cell nucleus (1). Stat3 is constitutively activated in a number of human tumors (3). Stat3-activated transcription seems to be regulated by serine phosphorylation at Ser727 (4).|
Delta-Notch Signaling Pathway
EGFR1 Signaling Pathway
Jak-STAT signaling pathway
TGF Beta Signaling Pathway
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Western blot - Anti-STAT3 (phospho S727) antibody [E121-31]; .developed using the ECL technique.Performed under reducing conditions.Predicted band size : 88 kDa.Exposure time : 16 minutes
Western blot - STAT3 (phospho S727) antibody [E121-31]; All lanes : Anti-STAT3 (phospho S727) antibody [E121-31] at 1/1000 dilution.Lane 1 : A431 cell lysate.Lane 2 : A431 + EGF cell lysate.Predicted band size : 88 kDa.Observed band size : 98 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - STAT3 (phospho S727) antibody [E121-31]; IHC-P analysis of brain astrocytoma using ab32143 at 1/50 dilution.