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Anti-STAT2 Antibody EP1814Y
Also for STAT2 (NM_019963)
|A synthetic peptide corresponding to residues near C-terminus of mouse Stat-2 was used as immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:2000; IHC-P: 1:50 - 1:100; FC: 1:50
|Does not react with Rat, Human. Is unsuitable for ICC or IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Is unsuitable for ICC or IP.
|Mus musculus signal transducer and activator of transcription 2 (Stat2)|
|The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. [provided by RefSeq]. |
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Western blot - Anti-STAT2 antibody [EP1814Y]; Anti-STAT2 antibody [EP1814Y] at 1/2000 dilution + NIH 3T3 cell lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 105 kDa.