Anti-STAT1 Antibody, clone 15H3

Also for STAT1 (NM_139266)

OriGene Data

Immunogen	Protein expressed in 293T cell transfected with human STAT1 expression vector
Clone Name	clone 15H3	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB 1:2000 IHC 1:50 IF 1:100
Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens signal transducer and activator of transcription 1, 91kDa (STAT1), transcript variant beta
Alternative Name	CANDF7; ISGF-3; STAT91
Database Link	NP_644671
Function	The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Related Pathway	Adipogenesis EGFR1 Signaling Pathway Jak-STAT signaling pathway TGF Beta Signaling Pathway Toll-like receptor signaling pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STAT1 (RC201075, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-STAT1.

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-STAT1mouse monoclonal antibody. (TA500566, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of pancreas tissue using anti-STAT1mouse monoclonal antibody. (TA500566, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid tissue using anti-STAT1mouse monoclonal antibody. (TA500566, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of bladder tissue using anti-STAT1mouse monoclonal antibody. (TA500566, Dilution 1:50)

IF Image

Anti-STAT1 mouse monoclonal antibody (TA500566) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY STAT1(RC201075).

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

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Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-STAT1 TrueMAB Antibody clone 15H3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data