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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]

Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]

Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]

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Home Antibody UltraMAB

UltraMAB

SQSTM1 UltraMAB Antibody, Clone UMAB12

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Datasheet Price Availability*  
UM500012
  • Purified SQSTM1 mouse monoclonal antibody,clone UMAB12, 100 ul
$468 In Stock Add to Shopping Cart
UM570012
  • Purified SQSTM1 mouse monoclonal antibody,clone UMAB12, 30 ul
$120 In Stock Add to Shopping Cart
WB(1)
IHC(5)
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Also for SQSTM1 (NM_003900)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens sequestosome 1 (SQSTM1), transcript variant 1
SynonymsA170; OSIL; p60; p62; p62B; PDB3; ZIP3
ImmunogenFull length human recombinant protein of human SQSTM1(NP_003891) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone UMAB12 IsotypeIgG2b
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC Suggested DilutionsWB 1:500~2000, IHC 1:150,
BackgroundThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq].

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SQSTM1 monoclonal antibody (Clone UMAB12) at 1:500.
IHC Image
Immunohistochemical staining of paraffin-embedded breast tissue using anti-SQSTM1 mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded colon tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded liver tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)

 

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