OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431.
[anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780.
[SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052
[anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210.
[NPR3]
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SQSTM1 UltraMAB Antibody, Clone UMAB12
UltraMAB Antibodies - Validated with 10K Protein Chip
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SQSTM1 monoclonal antibody (Clone UMAB12) at 1:500.
Immunohistochemical staining of paraffin-embedded breast tissue using anti-SQSTM1 mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
Immunohistochemical staining of paraffin-embedded colon tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
Immunohistochemical staining of paraffin-embedded liver tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
Also for SQSTM1 (NM_003900)
Homo sapiens sequestosome 1 (SQSTM1), transcript variant 1
A170; OSIL; p60; p62; p62B; PDB3; ZIP3
Full length human recombinant protein of human SQSTM1(NP_003891) produced in HEK293T cell.
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone UMAB12
IgG2b
Human
0.5~1.0 mg/ml (Lot Dependent)
Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose )
WB, IHC
WB 1:500~2000, IHC 1:150,
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq].
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WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SQSTM1 monoclonal antibody (Clone UMAB12) at 1:500.
IHC Image
Immunohistochemical staining of paraffin-embedded breast tissue using anti-SQSTM1 mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded colon tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded liver tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
IHC Image
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-SQSTM1mouse monoclonal antibody. (Clone UMAB12, Dilution 1:100)
Conjugation Services OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)