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Anti-SPG7 TRUEMAB Antibody Clone OTI1D2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA504423 SPG7 mouse monoclonal antibody, clone OTI1D2 (formerly 1D2) 100ul 325
In Stock
LC401085 SPG7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504423 Carrier-free (BSA/glycerol-free) SPG7 mouse monoclonal antibody, clone OTI1D2 (formerly 1D2) 100ug $450 8-10 Days
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OriGene Data

ImmunogenHuman recombinant protein fragment correspongding to amino acids 300-573 of human SPG7(NP_003110) produced in E.coli.
Clone NameClone OTI1D2 IsotypeIgG1
Species ReactivityHuman Concentration0.68 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 88.1 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens spastic paraplegia 7 (pure and complicated autosomal recessive) (SPG7), transcript variant 1
Alternative NameCAR; CMAR; PGN; SPG5C
Database LinkNP_003110
Entrez Gene 6687 Human
FunctionThis gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq, Jul 2008].
Related PathwayTransmembraneProtease

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WB Image
Negative control E. coli lysate (Left lane) or E. coli lysate containing recombinant protein fragment for human SPG7(NP_003110) gene (amino acids 300-573) (Right lane). Equivalent amounts (5 ug per lane) were separated by SDS-PAGE and then immunoblotted with anti-SPG7.


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