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Home Antibody All anti-SOCS2 antibodies

Anti-SOCS2 Antibody EPR2588(2)


Specifications Citations (1) Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307336 Rabbit monoclonal antibody against SOCS2(clone EPR2588(2)) 100ul $325 In Stock
LC401278 SOCS2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human SOCS2 was used as an immunogen.
Clone NameEPR2588(2) IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 22 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens suppressor of cytokine signaling 2 (SOCS2), transcript variant 1
Alternative NameCIS2; Cish2; SOCS-2; SSI-2; SSI2; STATI2
Database LinkNP_003868
Entrez Gene 8835 Human
FunctionSOCS2 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of SOCS2 can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. SOCS2 is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control (1).
Related PathwayDruggable Genome Jak-STAT signaling pathwayInsulin signaling pathwayType II diabetes mellitus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - SOCS2 antibody [EPR2588(2)]; All lanes : Anti-SOCS2 antibody [EPR2588(2)] at 1/1000 dilution.Lane 1 : MCF7 cell lysate.Lane 2 : NCCIT cell lysate.Lane 3 : K562 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 22 kDa.

WB Image
Figure from citation: Western Blot of SOCS2 protein level by using anti-SOCS2 antibody in human CRC and distant normal counterpart tissues. Dilution: 1:1000 View Citation

IF Image
Immunocytochemistry/ Immunofluorescence - SOCS2 antibody [EPR2588(2)]; Immunofluorescent staining of HeLa cells using TA307336 at 1/100 dilution.


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