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Home Antibody All anti-SNCA antibodies

Anti-SNCA Antibody 3H9

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309078
  • Mouse Anti-alpha Synuclein Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400127) , 20ug Explanation
100ul 325 In Stock
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WB(1)
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Also for SNCA (NM_000345)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human alpha synuclein expressed in E. Coli.
Clone Name3H9 IsotypeIgG
Species Reactivityhuman, mouse, rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1,000, IF: 1:500
BufferAscites fluid + 0.01 % NaN3.
Purification Ascites fluid

Reference Data

Target NameHomo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 1
Alternative NameNACP; PARK1; PARK4; PD1
Database LinkNP_000336
Entrez Gene 6622 Human
Entrez Gene 20617 Mouse
Entrez Gene 29219 Rat
FunctionAlpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq].
Related PathwayDruggable Genome Alzheimer's diseaseParkinson's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot of a rat brain lysate showing specific immunolabeling of the ~15k alpha synuclein protein

 

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