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Home Antibody All anti-SLC7A8 antibodies

Anti-SLC7A8 TRUEMAB Antibody Clone OTI2D4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA500631 anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI2D4 (formerly 2D4) 100ul 325
In Stock
CF500631 Carrier-free (BSA/glycerol-free) SLC7A8 mouse monoclonal antibody, clone OTI2D4 (formerly 2D4) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human SLC7A8 (NP_036376) produced in HEK293T cell.
Clone NameClone OTI2D4 IsotypeIgG1
Species ReactivityHuman Concentration0.91 mg/ml
Guaranteed Application *IF, FC Suggested DilutionsIF 1:100, FLOW 1:100,
Predicted MW Explanation 58.4 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens solute carrier family 7 (amino acid transporter light chain, L system), member 8 (SLC7A8), transcript variant 1
Alternative NameLAT2; LPI-PC1
Database LinkNP_036376
Entrez Gene 23428 Human
FunctionSodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine orD,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.
Related PathwayTransmembraneDruggable Genome

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IF Image
Anti-SLC7A8 mouse monoclonal antibody (TA500631) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SLC7A8(RC208586).

FC Image
HEK293T cells transfected with either RC208586 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SLC7A8 antibody(TA500631), and then analyzed by flow cytometry.


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